The aim of this study is to highlight that scientific substantiation, extensive theoretical knowledge, practical experiences and expertise are all indispensable elements for the development of a well-functioning, professional profiling procedure and related researches. With partial results of an ongoing research and a review of the results of other researches, I try to prove that statistical profiling is a viable method for profiling perpetrators of homicides. However, a profile with a statistical approach may not be the only method that can be used. Using only statistical procedures would ignore the complexity of offender behaviour, and there would be no need for profiling professionals with behavioural science knowledge. The solution could be a multidisciplinary, mixed approach. Regardless of the approach taken, without incorporating law enforcement knowledge, crime scene investigation and investigative knowledge into research - although they might come through in the scientific community - their practical applicability may become questionable.