Dr. Mátyás Hegyaljai, Deputy State Secretary for EU and International Affairs of Ministry of Interior (Hungary), is the interviewee in our thematic issue commemorating the 100th anniversary of INTERPOL. Mr. Hegyaljai’s name may ring a bell not only for our Hungarian readers but also for our foreign readers, as he was the head of the Hungarian INTERPOL National Central Bureau, a member and then President of the INTERPOL European Commission and later a member of the INTERPOL Executive Committee. During the interview we discussed the global, regional and national aspects of law enforcement, the importance of regional – including European – cooperation, the impact of the digital revolution and the COVID epidemic, Hungary’s role in combating crime, and Mr Hegyaljai’s personal experiences. The Deputy State Secretary was interviewed by Prof. Dr Valér Dános, Editor-in-Chief, and Dr Csaba Szabó, Deputy Editor-in-Chief.